Cleaved gsdmd antibody
WebMay 4, 2024 · Cleaved GSDMD forms membrane pores, leading to cytokine release and inflammatory cell death (pyroptosis). ... The monoclonal antibody against GSDMD was generated in house by immunizing 6-week-old ... WebKeyword:'anti cleaved n-terminal gsdmd antibody' Showing 1-7 of 7 results for "anti cleaved n-terminal gsdmd antibody" within Products. Products Genes Papers Technical Documents Site Content Chromatograms. Filter & Sort. All Photos (1) Anti-CATG (Cleaved-Ile 21), N-Terminal antibody produced in rabbit. Synonym(s): CG, CTSG, Cathepsin G.
Cleaved gsdmd antibody
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WebAll lanes : Anti-cleaved C-terminal GSDMD antibody [EPR20859-147] at 1/1000 dilution Lane 1 : iBMM (mouse immortalized bone marrow derived macrophages) treated with 500ng/ml Bsak plus 500ng/ml anthrax protective antigen (PA) for 2h. Cell lysate Lane 2 : iBMM (mouse immortalized bone marrow derived macrophages) treated with 500ng/ml … WebJul 7, 2016 · Inflammatory caspases (caspases 1, 4, 5 and 11) are activated in response to microbial infection and danger signals. When activated, they cleave mouse and human gasdermin D (GSDMD) after Asp276 and Asp275, respectively, to generate an N-terminal cleavage product (GSDMD-NT) that triggers inflammatory death (pyroptosis) and release …
WebDec 23, 2024 · The cleavage of caspase-1 was observed at 3 and 6 h after the treatment of rmCIRP (1 µg/ml). The Western blot of cleaved caspase-1 was detected first. Full-length GSDMD and β-actin were probed at the same time after stripping the anti-cleaved GSDMD antibody. The intensity of bands detected was quantified by densitometry. WebWestern blot - Anti-cleaved C-terminal GSDMD antibody [EPR20859-147] - BSA and Azide free (ab255985) All lanes : Anti-cleaved C-terminal GSDMD antibody [EPR20859-147] ( …
WebAnti-cleaved C-terminal GSDMD antibody [EPR20885-203] (ab227821) Description: Rabbit monoclonal [EPR20885-203] to cleaved C-terminal GSDMD. Application: WB. Reactivity: Human. Conjugate: Unconjugated. Recombinant. Human GSDMD ELISA Kit (ab272463) Description: Human GSDMD ELISA Kit. Reactivity: Human. WebMonoclonal Antibody for studying gasdermin D (Asp276,C-term) cleaved mouse. Cited in 18 publications. Validated for Western Blotting. Highly specific and rigorously validated in …
WebOur GSDMD polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit and Mouse. Find the GSDMD antibody that fits your needs. Choose from 1 of 18 GSDMD antibodies, which …
Web经典一抗-Cleaved-Caspase 4 (Gln81), p20 Antibody. Datasheet. Description. ... Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium ... semcip stan websiteWebGasdermin-D (also known as GSDMD), the newly identified executioner of pyroptotic cell death, is cleaved by activated caspase-1 downstream of canonical inflammasome activation or caspase-4, 5, and 11 upon their ligation and activation by cytosolic LPS. Upon a single cleavage between the two domains in Gasdermin-D, the N-terminal domain binds to ... semcip websiteWebAug 29, 2024 · The specificity of the cleaved GSDMD antibody for the active peptide has been previously validated and was further confirmed using nigericin-treated wild-type and GSDMD knock-out THP-1 cell lines (kindly provided by Dr. Daniel Muruve, University of Calgary) (Supplemental Figure 1A). Using ... semcl softballWebAug 23, 2024 · product name : Anti-cleaved N-terminal GSDMD antibody [EPR20829-408] catalog : ab215203 quantity : 10 UL,40 UL,100 UL clonality : monoclonal host : domestic … semcip technical assistance network stanWebGasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] semcip technical assistance networkWeb66387-1-Ig targets GSDMD in WB, IF, ELISA applications and shows reactivity with human samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. … semco application systems mixerWebSep 16, 2015 · GSDMD is specifically cleaved by caspase-1/4/5/11. The above analyses predict that GSDMD functions downstream of the inflammatory caspases. We observed … semco battery injection gun