WebWhat is the action of filgrastim (Neupogen)? What is the action of epoetin alfa (Epogen)? Review Box 43.1 on Cancer Care. Review the adverse effects of chemotherapy and appropriate nursing assessment and interventions needed. WebFilgrastim is a glycoprotein that binds to and stimulates neutrophils to divide and differentiate. Also activates mature neutrophils. Binding to a polyethylene glycol molecule prolongs its effects. ... legs, or abdomen. Report these signs to the physician or nursing staff immediately. Watch for signs of spleen rupture, including pain and ...
Bone Marrow Suppression Nurse Key
WebNursing Implications. Assessment & Drug Effects. Monitor urine for hematuria. Be aware that a false-positive test for urinary ketones may arise in patients treated with mesna. In this test, a red-violet color develops that, with the addition of glacial acetic acid, will turn to violet. Web* Dosage modification may be necessary if WBC > 100.000 cells/mm3 (infection precautions) Which of the following adverse effects should the nurse discuss with a patient receiving filgrastim? 1.Fatigue 2.Bleeding 3.Headache 4.Bone pain 4.Bone pain Students also viewed Filgrastim 11 terms langes5 filgrastim 8 terms ayeager0507 sign on bonus for checking account
Filgrastim (Neupogen) - Side Effects, Interactions, Uses, Dosage ...
WebThe most common side effect of Neupogen ® is mild to moderate bone pain. Other possible side effects of Neupogen ® include fever, diarrhea, skin rash and weakness. … Human granulocyte colony-stimulating factor (G-CSF) produced by recombinant DNA technology. Endogenous G-CSF regulates the production of neutrophils within the bone marrow; not species specific and primarily affects neutrophil proliferation, differentiation and selected end-cell functional activity (including … See more To decrease the incidence of infection, as manifested by febrile neutropenia, in patients with nonmyeloid malignancies receiving myelosuppressive anticancer drugs associated with a significant incidence of severe … See more Assessment & Drug Effects 1. Lab tests: Obtain a baseline CBC with differential and platelet count prior to administering drug. Obtain CBC twice weekly during therapy to monitor neutrophil count and leukocytosis. Monitor … See more Hypersensitivity to Escherichia coli–derived proteins, simultaneous administration with chemotherapy, and myeloid cancers. See more Elevations in leukocyte alkaline phosphatase, serum alkaline phosphatase, lactate dehydrogenase, and uric acidhave been … See more theradbrad alien isolation